Abstract:

Purpose: Complete blood count parameters have been investigated as a predictor of inflammatory process in many diseases, but their role in osteoarthritis is unclear. The aim of present study was to investigate the diagnostic value of routine hematological parameters on osteoarthritis and to explore their clinical significance.  Material and Methods: The study included 118 patients with osteoarthritis and 145 healthy individuals. Medical records, Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), white blood cell count (WBC), neutrophil-lymphocyte ratio (NLR), platelet count, platelet distribution width (PDW), red cell distribution width (RDW), RDW-platelet ratio (RPR), platelet-lymphocyte ratio (PLR) and mean platelet volume (MPV) levels were retrospectively recorded from patient files. Results: There were no significant differences in WBC, RDW, PLT, RPR levels between two groups. NLR and PLR values were significantly higher in the osteoarthritis group than in the control group. RBC, MPV and PDW values were significantly lower in the osteoarthritis group than in the control group (all . MPV and RBC were negatively correlated with ESR and CRP in osteoarthritis patients.  Conclusion: Hematological inflammatory markers might be useful parameters that could be used in patients with osteoarthritis.

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