Özet:

Objective: The importance of multiparametric magnetic resonance imaging (mpMRI) in the diagnosis of prostate cancer (PCa) and in its differentiation from non-cancerous prostate diseases (NCPD) was evaluated. Material Method: Images of 99 patients who underwent mpMRI with a pre-diagnosis of PCa between December 2017 and January 2020 were retrospectively evaluated. The MpMRG acquisition protocol consisted of T2W TSE (axial-coronal-sagittal), T1W TSE (axial-coronal-sagittal), diffusion-weighted imaging (DWI) and T1W dynamic contrast imaging (DCI) sequences. The location, morphology, extraprostatic spread (EPY) of the lesions, T2W signal intensity (T2SI) values, diffusion restriction, enhancement curve patterns, maximum enhancement value (Cmax), time to reach maximum enhancement (acceleration time: AZ) were evaluated. The relationship between the findings was evaluated using the SPSS 20.0 program. Results: 75 of 99 cases were diagnosed as Prostate Ca (PCa), 24 of them had NCPD hitopathological diagnosis. The age ratio of all patients was 66.5 ± 7.4. A significant difference was found between the apparent diffusion coefficient (ADC) (p <0.001), Cmax and AT (p <0.005) values, PCa and KDPH groups in lesions located in the peripheral zone. T2SI values of lesions in the transitional zone differed significantly between patient groups (p <0.001). The Type 1 curve for PCa and the Type 3 curve for NCPD were found to be significant in terms of differential diagnosis (p <0.002). In transitional zone lesions, T2SI decreased as the curve type shifted to the malignant side. As the degree of EPY increased, an increase was found in the near invasion rates (p <0.001). Conclusion: Multiparametric prostate MRI is an extremely valuable radiological diagnostic method in distinguishing PCa from NCPD and revealing the local invasion status. ADC, T2SI and DCE quantitative values play an important role in the prediction of benign-malignant lesions.

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