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3
A 12 month old male baby with diagnoses of Down syndrome and complete atrioventricular canal defect underwent total correction. His early postoperative course was complicated with pulmonary hypertensive crises. It was initially treated by 40-60 ppm inhaled nitric oxide (iNO), but we had to decrease the dosage because of serum increased methemoglobin levels after 24 hours of treatment (10 ppm). We added oral sildenafil sitrate as a combination therapy (6 mg/kg/day) which was seemed to be effective in controlling pulmonary hypertensive crises. Combined regimens like iNO and sildenafil for postoperative pulmonary hypertensive crises are beneficial in terms of reducing the dosage of iNO and preventing rebound pulmonary hypertension.
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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