Özet:

Purpose: Different indications, doses, methods of application, age group, specific population, etc. Their use is called "non-indicated drug use" (EDIC). In this study, EDIK was intended to be studied in different provinces and regions in Turkey. Method: In 2011 a total of 5681 applications for EDIK applications to the Turkish Medicine and Medical Equipment Institute were examined. These applications are at the NUTS-1 (Nomenclature of Territorial Units for Statistics) regional level; the patient’s age, gender, place, time of application, etc. It was detailed in terms of its characteristics and the first five most frequently applied medications in each region. Results: 81.6% of EDIC applications come from university hospitals and the number of applications is 2 calendar year. It was concentrated in the quarter. The average age of patients applied in all other NUTS-1 regions except in the southeastern Anadolu region was over 30 and the majority of patients (55.1%) were women. On corporate level, the most frequent EDIK applications were made from the West Anadolu Region (34.9%) and followed by the regions of Istanbul (26.5%) and Ege (10.3%). On the basis of the insights, the application rate per 1000 specialist doctors was the most Chankırı (778,8), and at least in Istanbul (20,0) was determined. When the most frequently applied medications in each region were examined, the rankings varied between regions and the most frequently found medications were "rituksimab", "mikofenolate mofetil" and "iloprost trometamol". Result: The rational use of EDIK depends on some critical factors, including local characteristics. The differences in the counties and regions of the EDIC applications were first shown by this study. In increasing the functionality of the EDIC, these differences should be taken into account. These findings are expected to keep light on new studies and regulations that will directly reveal the causes of these differences.