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Abstract Introduction: With the objective of creating an observatory of the health services that served as a reference to monitor and report adverse events and technical complaints in the post-use of products subject to sanitary surveillance, the Brazilian Health Regulatory Agency (Anvisa) initiated, in 2002, the Sentinel Network Project. Objective: To verify the Network profile in the year 2016, guiding the Agency for planning new accreditations. Method: Descriptive and quantitative study, elaborated from the collection of information from documents sent to Anvisa, by health institutions. Results: The Network has 221 accredited institutions, corres-ponding to 3.0% of Brazilian hospitals. These services are in 24 out of 27 federative units in Brazil, 56.0% are large hospitals and 24.0% are medium-sized hospitals. Among the 50 federal university hospitals, 23 joined the Sentinel Network and, from which, 19 are currently admi-nistered by the Brazilian Hospital Services Company (EBSERH). Within the Network, there are 161 general hospitals and 60 specialized institutions. It is noteworthy that 126 institutions of the Sentinel Network are certified as teaching hospitals, which represents 64% of hospitals certified by the Ministry of Education (MEC). Conclusions: It is important to have a continuous reflection about the representativeness of the group of Sentinel hospitals in Brazil with a view to the continuous improvement of post-marketing surveillance. In this sense, it is necessary to make efforts to accredit other hospitals, even in the states without representation, as well as to develop new strategies for strengthening the Network. Author Biography Ana Paula Coelho Penna Teixeira, Agência Nacional de Vigilância Sanitária (Anvisa), Brasília, DF Gerência Geral de Monitoramento de Produtos Sujeitos à Vigilância Sanitária -  Gerência de Hemo Bio vigilância e outros produtos sujeitos à Vigilância Sanitária

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