Özet:

In the present study, it was aimed to investigate the effect of intraperitoneal and incisional sprayed lidocaine on postoperative stress, oxidative stress and pain in dogs undergoing ovariohysterectomy. The control group (n=12) received intraperitoneal and incisional sprayed 0.9 % NaCl, whereas the preparation of lidocaine (8.8 mg/kg) with the equal volume of 0.9 % NaCl following calculation of the individual doses was sprayed in the experiment group (n=12). Modified Melbourne pain assessment was performed before sedation (T), at the end of surgery (T0), 30 minutes after surgery (T½) and at 1 (T1), 2 (T2), 4 (T4) and 6 (T6) hours after the end of surgery. Venous blood samples were collected to measure the concentrations of serum cortisol, total oxidant status (TOS) and total antioxidant status (TAS) at related times. Oxidative stress index (OSI) was calculated by the determination of the rate of TOS/TAS. The concentrations of cortisol, TAS and OSI did not show any significant difference between groups (p > 0.05). The concentration of TOS was the highest at T1 in the experiment group (p<0.05). The pain scores in the experiment group were lower (p<0.05) than those detected at T2 (p<0.05), T4 (p<0.01) and T6 (p<0.01) in the control group. In conclusion, it was stated that the treatment of intraperitoneal and incisional sprayed lidocaine is effective on postoperative pain management in dogs undergoing ovariohysterectomy.

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