Özet:

Geriatric population (>80 years) has an increased mortality risk due to several reasons including more extensive coronary artery disease (CAD) and impaired renal function. We investigated the relationship between in-hospital mortality and renal dysfunction in geriatric patients with ST-elevation myocardial infarction (STEMI) who underwent primary percutaneous intervention (PCI). We included 203 geriatric patients with STEMI who underwent primary PCI. Patients were divided into 2 groups; group 1 comprised 42 patients who died in the hospital after MI, and group 2 included 161 patients who were discharged following primary PCI. The risk factors of the patients were determined. We calculated coronary artery disease prevalence by Gensini risk score, renal function by creatinine clearance (CrCl), and compared 2 groups. The patients in group 1 who died in hospital after STEMI were older; they had more extensive CAD and lower CrCl (age: 82 ± 5 yr, 78 ± 7 yr, p<0.001; Gensini score: 70 ± 30, 42 ± 26, p: 0.001; CrCl: 46 ± 17 mL/min, 65 ± 18 mL/min, p<0.001). When multivariate analysis was performed with logistic regression, we found to be CrCl, HDL-cholesterol, and Gensini scores to be the independent predictors of in-hospital mortality (CCL: OR 1.057 (1.029-1.086), p = 0.001); HDL: OR 1.077 (1.021-1.136), p = 0.007, Gensini score: OR 0.969 (0.952-0.985), p = 0.001). Renal dysfunction increases in-hospital mortality in elderly patients with STEMI undergoing primary PCI. Renal dysfunction in elderly patients with MI is an important risk factor that increases in-hospital mortality like other cardiovascular risk factors.

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