Özet:

Aim: This study purposed to evaluate thyroid hormone levels and work-related factors in workers. Materials and Methods: This retrospective study was perfomed at 475 workers who applied to the outpatient clinic of occupational diseases between November 2015-February 2020. Sociodemographic variables, work-related factors and laboratory records were retrospectively evaluated. Student’s t-test was performed to compare mean values. Multiple linear regression analysis was used, including independent variables that were found to be statistically significantly related in binary analysis of thyroid-stimulating hormone (TSH) value. Results: Of the 475 participants, 433 (91.2%) were male and 173 (36.4%) worked night shifts, 293 (61.7%) were exposed to silica dust, 23 (4.8%) to plastic fumes, and 80 (16.8%) to solvent. Study participants who were over 40 years of age, night shift workers, and workers with exposure to silica dust had significantly lower TSH values (p=0.026, p=0.023, p=0.002, respectively); male workers, workers under 40 years of age, and workers with body mass index (BMI) <25 had significantly higher free T4 levels (p=0.017, p=0.042, p=0.026, respectively). In the regression analysis, it was observed that there was a significant relationship BMI, silica dust exposure, night shift work and low TSH level (p=0.033, p=0.028, p=0.045). Conclusion: It was found that night shift work and exposure to silica dust were associated with decreased TSH levels in workers. Silica dust exposure and night shift work are among the preventable risk factors. For this reason, the workplace environment should be reorganized, periodic health examinations should be carried out, and workers should be ensured to comply with occupational health and safety rules.

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