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Amaç: Bu çalışmanın amacı etyololojisi halen tam olarak bilinmeyen Bell’s Palsy de inflamasyon belirteci olan Nötrofil/Lenfosit oranı (NLO), Platelet/Lenfosit oranı (PLO) ve Ortalama Platelet Hacminin (OTH) nasıl değişim gösterdiğini araştırmak ve çocuklardaki Bell’s Palsy de inflamasyonun olası etkisini araştırmaktır. Gereç ve Yöntem: Bu retrospektif çalışmaya hastanemizde Ocak 2010 ile Mayıs 2018 tarihleri arasında Bell’s Palsy tanısı alarak tedavisi ve takibi yapılmış 27 çocuk hasta ile 25 sağlıklı birey dahil edilmiştir. Hastaların tedaviden önceki ve sonraki Bell’s Palsy lerinin klinik derecelendirilmesinde House–Brackmann sınıflaması kullanılmıştır. Bu çalışmada hastaların tedaviden önce rutin olarak yapılmış hemogram tetkiklerinden NLO, PLO ve OTH değerlerinin ortalamaları ve kontrol grubunun bu ortalama değerleri karşılaştırılmıştır. Bulgular: Bell’s Palsy grubundaki çocukların ortalama yaşları 9,76±3,71 iken kontrol grubunda ortalama yaş 9,48±3,54 idi. Bell’s Palsy grubundaki hastaların 15 i kadın 12 si erkek iken kontrol grubundaki hastaların 14 ü kadın 11 i erkekti. Tedaviden önceki NLO değeri Bell’s Palsy grubunda 2,71±1,53 iken kontrol grubunda 1,51±1,27 bulundu. Bell’s Palsy grubunda NLO değeri kontrol grubuna göre istatiksel olarak anlamlı düzeyde yüksekti (p<0,05). PLO değeri açısından iki grup arasında istatistiksel fark izlenmedi (p>0,05). OTH değerleri açısından da iki grup arasında istatistiksel fark izlenmedi (p>0,05). Sonuç: Çalışmamız daki Bell’s Palsyli çocuklarda NLO nun kontrol grubuna göre anlamlı düzeyde artışı çocuklardaki Bell’s Palsy de inflamatuar teoriyi desteklemektedir. Çocuklarda Bell’s Palsy de ise PLO ve OTH ilk kez tanımlanmıştır.
Purpose: The aim of this study is to explore how the ethology of Bell's Palsy, which is still unknown, is the inflammatory indicator of the neutrophil/lenphocytes rate (NLO), the platelet/lenphocytes rate (PLO) and the average platelet volume (OTH), and to explore the possible effects of the inflammation in children. This retrospective study included 25 healthy individuals with 27 children who were treated and traced by Bell's Palsy diagnosis in our hospital between January 2010 and May 2018. The clinical classification of Bell's Palsy before and after treatment was used by House-Brackmann classification. This study compared the average NLO, PLO and OTH values and the average values of the control group from patients' routine hemogram examinations before treatment. Results: The average age of children in the Bell's Palsy group was 9.76±3.71, while the average age in the control group was 9.48±3.54. 15 of the patients in the Bell's Palsy group were female and 12 male, while 14 of the patients in the control group were female and 11 male. The pre-treatment NLO value was 2,71±1,53 in the Bell's Palsy group, while 1,51±1,27 in the control group. In the Bell's Palsy group, the NLO value increased statistically significantly compared to the control group (p<0,05). There was no statistical difference between the two groups in terms of the PLO value (p>0,05). There was no statistical difference between the two groups in terms of OTH values (p>0,05). The result: Bell's Palsy in our study also supports the inflammatory theory of a significant increase in levels according to the control group of the NLO in children. Bell's Palsy is the first time identified with PLO and OTH.
Objective: The aim of this study is to investigate how Neutrophil/Lymphocyte (NLR), Platelet/Lymphocyte ratios (PLR) and Mean Platelet Volume(MPV) which are indicators of inflammation show change, and likely effects of inflammation in etiology of Bell’s Palsy which is not put forth totally yet. Materials and Methods: This retrospective case controlled study included 27 pediatric patient diagnosed as Bell’s Palsy, treated and followed between january 2010 and may 2018 and 25 healthy children in our hospital. House–Brackmann classification was used in Bell’s Palsy graduation before and after their treatment. In this study, mean values of Neutrophil counts, Lymphocyte counts, Platelet counts, Neutrophil/ Lymphocyte , Platelet/Lymphocyte ratios and Mean Platelet Volumes were compared in complete blood count samples drawn for rutine assays of patient and controls. Results: While the mean age in patient group was 9,76±3,71, in control group it was 9,48±3,54. Patient group consisted of 12 male and 15 female patiens and controls included 11 male and 14 female. Before the treatment NLR was 2,71±1,53 in patients and ,1,51±1,27 in control group. In patient group the NLR was statistically significantly higher than that of control (p<0,05). In terms of PLR and MPV, there was no statistical significance between both groups (p>0,05). Conclusion: In Bell’s Palsy of children, the PLR and MPV were identified for the first time by our study and statistically significantly increased levels of NLR in patients comparing controls supports inflammatory theory as well.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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