Özet:

INTRODUCTION: Objective: Nosocomial sepsis is among the major factors contributing to mortality in intensive care units (ICUs). Mortality predictors in general ICU patients with nosocomial sepsis were investigated. METHODS: This retrospective cohort study was conducted between January 1, 2013 and May 1, 2014 in two general ICUs of a training and research hospital. In total, 95 sepsis attacks developing in 83 patients were included. Data from patient medical records were recorded on standardised forms. RESULTS: The incidence of sepsis was 21.2 cases per 100 ICU admissions. The median length of stay in the ICU was 37.56±39.595 (range, 1-173) days. Of the patients, 43 (51.8%) were males and 40 (48.2%) females. Their ages ranged from 18 to 90 (median, 69±15.753) years. The median APACHE II score was 26.9±6.4 (range, 15-45). The primary reasons for admission were medical problems in 62 (74.7%), elective surgeries in 13 (15.7%), and emergency surgeries in 10 (12.8%). Pneumonia (80%) accounted for the majority of nosocomial sepsis cases in the ICUs. Pseudomonas aeruginosa (24.6%), Acinetobacter baumannii (24.6%), and Klebsiella pneumoniae (18.5%) were the most commonly identified microorganisms. The final multivariate logistic regression showed that emergency surgery (P = 0.004), an increase in the SOFA score (P= 0.001), and haemodialysis required for acute renal failure (P = 0.004) were statistically significant risk factors for mortality due to nosocomial sepsis. DISCUSSION AND CONCLUSION: Monitoring SOFA scores may be useful for the follow up patients with nosocomial sepsis.

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