User Guide
Why can I only view 3 results?
You can also view all results when you are connected from the network of member institutions only. For non-member institutions, we are opening a 1-month free trial version if institution officials apply.
So many results that aren't mine?
References in many bibliographies are sometimes referred to as "Surname, I", so the citations of academics whose Surname and initials are the same may occasionally interfere. This problem is often the case with citation indexes all over the world.
How can I see only citations to my article?
After searching the name of your article, you can see the references to the article you selected as soon as you click on the details section.
 Views 18
 Downloands 6
Sol Ventrikül Hipertrofisinde (RRM1, RRM2, ERCC2) DNA Tamir Gen Polimorfizmleri
2019
Journal:  
Experimed
Author:  
Abstract:

DOI: 10.26650/experimed.2019.19024 Amaç: Sol Ventrikül Hipertrofisi (SVH) kardiak hastalıklar için sık görülen bir risk faktörüdür. Bu çalışmada DNA tamir gen polimorfi­zimleri ve sol ventrikül hipertrofisi arasındaki ilişkiyi araştırdık. Gereç ve Yöntem: Periferik kandan izole edilen DNA örnekleri RRM1 (rs12806698), RRM2 (rs6859180) ve ERCC2 (rs13181) genleri için Gerçek Zamanlı Polimeraz Zincir reaksiyon (GZ- PZR) ile genotiplendirildi. Bulgular: Kontrol ve hasta grupları arasında RRM2 (p=0,365) ve ERCC2 (p=0,740) genleri için önemli fark olmamasına rağmen, RRM1 (A>C) CC genotip frekansı SVH hastalarında kontrol grubuna göre anlamlı şekilde yüksek olarak bulundu (p=0,018). RRM1 geni yabani tip A allel taşıyıcıları sağlıklı kontrolde SVH li hastalara göre anlamlı şekilde yüksek olarak tespit edildi (p=0,029). Sonuç: RRM1 CC genotipi SVH’ne karşı bir risk faktörü olabilirken RRM1 AC genotipi ve A alleli koruyucu role sahip olabilir. Cite this article as: Akdeniz FT, Güleç Yılmaz S, İsbir CS, Birkan Y, Esensoy DS, Özcan G, et al. Preliminary Study: DNA Repair Gene Polymorphisms (RRM1, RRM2, ERCC2) In Left Ventricular Hypertrophy. Experimed 2019 9(3): 99-104.

Keywords:

Preliminary Study: Dna Repair Gene Polymorphisms (rrm1, Rrm2, Ercc2) In Left Ventricular Hypertrophy
2019
Journal:  
Experimed
Author:  
Abstract:

DOI: 10.26650/experimed.2019.19024 Objective: Left ventricular hypertrophy (LVH) accounts for one of the most important independent risk factors for cardiac diseases. In the present study, we investigate the relationship of DNA repair gene polymorphisms and LVH. Material and Method: DNA samples isolated from peripheral blood were genotyped with real-time polymerase chain reaction (RT-PCR) for RRM1 (rs12806698), RRM2 (rs6859180) and ERCC2 (rs13181) genes. Results: Although there were no significant differences for RRM2 (p=0.365) and ERCC2 (p=0.740) genes. RRM1 (A>C) CC genotype was significantly higher in the LVH than control groups (p=0.018). RRM1gene wild type A allele carriers were significantly higher in the healthy controls than the LVH group (p=0.029). Conclusion: RRM1 gene CC genotype could be a risk factor, whereas the RRM1 gene AC genotype and the A allele might play a protective role against LVH. Cite this article as: Akdeniz FT, Güleç Yılmaz S, İsbir CS, Birkan Y, Esensoy DS, Özcan G, et al. Preliminary Study: DNA Repair Gene Polymorphisms (RRM1, RRM2, ERCC2) In Left Ventricular Hypertrophy. Experimed 2019; 9(3): 99-104.

Keywords:

Citation Owners
Information: There is no ciation to this publication.
Similar Articles












Experimed

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

Metrics
Article : 245
Cite : 217
Experimed