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Investigation of Electrochemical Properties of UA At Al2O3NP/CPE and Development of Voltammetric Method for its Determination in Serum
2023
Journal:  
Hacettepe Journal of Biology and Chemistry
Author:  
Abstract:

The electrochemical properties of uric acid (UA) were determined by cyclic voltammetry (CV) and square wave voltammetry (SWV) at a carbon paste electrode modified with aluminum oxide nanoparticles (Al2O3NP/CPE) in 0.05 M pH 5.0 phosphate buffer. The adsorption properties of the molecule on Al2O3NP/CPE were investigated and the number of electrons transferred in the electrode reaction was calculated. A new voltammetric method for the determination of UA in human serum was also proposed. The linear operating range and limit of detection (LOD) of the method were found to be 0.1µM-230 µM and 0.1µM, respectively. The developed method for UA in serum showed high reliability, reproducibility, accuracy and precision.

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2023
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Hacettepe Journal of Biology and Chemistry

Field :   Fen Bilimleri ve Matematik

Journal Type :   Uluslararası

Metrics
Article : 779
Cite : 657
2023 Impact : 0.025
Hacettepe Journal of Biology and Chemistry