Abstract:

Our aim in our study is to compare radiotherapy with the diagnosis of pancreatic cancer, to 20 patients with consistent radiotherapy (3B-KRT), intensity-adjusted radiotherapy (IMRT), volume-adjusted arc therapy (VMAT) techniques with treatment planning and dozimetric comparison of techniques. In this study, 20 patients with primary pancreatic head tumor, which were treated in our clinic between 2012 and 2017, were evaluated as retrospective. For each patient, 5 different treatments for the tumor, tumor surroundings and regional lymphatic nodes are planned, all plans are selected so that the target volume doses will be 54/45 Gy. The plans are prepared using 6 MV X-ray for VMAT and IMRT, and 6/15 MV X-ray for 3BKRT. Planned target volume doses (PTV), Conformity Index (CI), Homogenity Index (HI), risky organs (birds, spinal cord, liver) are compared with techniques. The average CI index for PTV54 and PTV45 was 1,16 and 1,03 VMAT 2 respectively in the VMAT 1 ark plans and 1,01 and 1,00 respectively in the VMAT 2. Although there is no significant difference between the two groups in terms of CI, the appropriate CI value is found in the 2 ark plans (p=0,806-PTV54 for PTV45 for p=0,595). The difference between IMRT and 3B-KRT techniques has not been found in terms of CI, appropriate value is obtained from the IMRT technique. Although there is no statistical difference in critical organ doses between VMAT 1 ark and VMAT 2 ark plans, the doses of VMAT 2 ark plans have been found lower. Since pancreatic tumors are located close to critical organs such as kidneys and liver, 3BKRT plans can be accepted from the point of view of the liver; but the kidneys are not sufficient from the point of view of protection. The VMAT 2 ark technique has provided superiority in dosage yellow, CI, HI and critical organ doses compared to other techniques. Therefore, considering side effects, VMAT can be preferred as a therapeutic technique.

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