Özet:

Objective: Asthma is a chronic inflammatory disease of the airways. Allergic inflammation is characterized by accumulation of various cells, particularly mast cells, eosinophils, T lymphocytes and platelets. We investigated whether changes in mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT) and p-selectin levels of children with asthma during and at least 1 month after the attack can be used as a marker.Material and Methods: The study was performed in 40 children who suffered asthma attacks. Blood samples were taken for MPV, PDW, PCT, p-selectin, eosinophil and platelet values during and at least 1 month after the attack. Results: Mean platelet volume, PCT, and p-selectin levels were significantly lower at the time of the attack when compared to those at least 1 month after the attack. Conclusion: Our findings suggest that MPV and PCT, common parameters in routine practice, can be used to determine an asthma attack

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