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Nadir Bir Olgu: Aksiller Bölgede Malign Granüler Hücreli Tümör
2019
Journal:  
Bağcılar Tıp Bülteni
Author:  
Abstract:

Granüler hücreli tümör (GHT) nadir görülen yumuşak doku tümörüdür. Sıklıkla üst ekstremitede görülse de vücudun herhangi bir yerinde görülebilir. Tümör olgularının büyük çoğunluğu benigndir yaklaşık %2’lik kısmı maligndir. Tümör %5-8 oranında memede görülmektedir. Yavaş büyüyen, ağrısız, mobil kitle ile ortaya çıkar. Kesin tanı histopatolojik olarak konulmaktadır. Tedavisi geniş eksizyondur. Yetmiş beş yaşında kadın hasta sağ aksillada ülsere eksüdalı kitle ile başvurdu. Sekiz ay önce sağ memedeki mamografi sonucu BIRADS 3 olan kitle için genel cerrahi tarafından mastektomi ve aksiller diseksiyon yapıldı. Meme patolojisi filloides tümör olarak belirlendi. Aksilladaki otuz lenf nodundan beş tanesinde GHT’ye rastlandı. Aksilladaki kitleye insizyonel biyopsi yapıldı. Histopatolojik ölçümlerde S-100 ve CD-68 pozitifliği, tümör hücrelerinde eozinofilik boyanma ile belirgin nükleolusua sahip pleomorfik nükleuslar görülmüştür. Tümör geniş eksizyonla çıkartıldı defekt alanı kısmi kalınlıkta deri greft ile kapatıldı. Patolojik ölçümlerde aksilladaki GHT’nin meme metastazı olarak değil, deri kaynaklı malign GHT’si olduğu belirlendi. Ki-67 proliferasyon indeksi %10 olarak saptandı. Cerrahi sınırlar salim olarak görüldü. Hastanın postoperatif takiplerinde herhangi bir komplikasyona rastlanmadı. Aksilladaki GHT’ler genel olarak meme metastazı sonucu görülmektedir ve büyük çoğunluğu benigndir. Malign deri kaynaklı GHT nadir görülen bir olgudur.

Keywords:

A rare fact: malignant granular cell tumor in the axil area
2019
Author:  
Abstract:

Granular cell tumor (GHT) is a rare soft tissue tumor. It can often be seen in the upper limb, but it can be seen anywhere in the body. The majority of tumor cases are self-sufficient and about 2% are malignant. The tumor is observed in the breast by 5-8%. It appears with slowly growing, painless, mobile masses. The exact diagnosis is histopathological. The treatment is extensive. Seventy-five-year-old woman, who was sick in the right axil, applied to the mouths with an exhausted mass. Eight months ago the result of mammography in the right breast was BIRADS 3 by general surgery for the mass was made mastectomy and acne disection. Breast pathology was identified as filloides tumor. Five of the thirty lymph nodes in the axile were found to GHT. A biopsy was performed in the insecticus. In histopathological measurements, S-100 and CD-68 positivity were observed in the tumor cells with eozinofyl coloring and clear nucleolusua of pleomorphic nucleus. The tumor was removed with a wide excision and the defect area was partially closed with a skin greft in the thickness. In pathological measurements, the GHT in the axil was determined to be malignant GHT from the skin, not as a breast metastasis. The Ki-67 proliferation index was 10%. The surgical limits were seen as healthy. No complications were observed in the postoperative follow-up of the patient. GHTs in the axil are generally seen as a result of breast metastasis and the vast majority of them are selfish. Malign skin GHT is a rare phenomenon.

Keywords:

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Bağcılar Tıp Bülteni

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

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Article : 284
Cite : 6
Bağcılar Tıp Bülteni