Özet:

Mucormycosis is a rare, opportunistic infection caused by Mucoroles, class Zygomycetes. It produces fatal infections in immunocomprised patients in the childhood. We describe two case of rhinocerebral mucormycosis in neutropenic patients with relapses. Case 1 (AD); 13 year-old-boy was diagnosed as acute lymphoblastic leukemia (ALL) and treated with BFM-95 protocol. He relapsed on his 21st month of maintenance therapy. Bone marrow aspiration showed acute myeloblastic leukemia (AML) and started AML treatment. After first induction therapy, he had suffered from febrile neutropenia. On 17th day of hospitalization, he had oral infection and biopsy specimen showed mucor infection. Case 2 (ZA); 14 year-old-girl. Bone marrow transplantation was done because of relapsed ALL. On 12st day after transplantation, she had had neutropenic period with necrotic lesion on her soft and hard palate with the diagnosis of mucor infection.

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