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DOI: 10.26650/IUITFD.344912 Objective: To evaluate maternal and fetal outcomes in pregnant women with systemic lupus erythematosus (SLE). Materials and Methods: This retrospective clinical study included 126 consecutive cases of pregnant women with SLE and was performed in the perinatology clinic of our university hospital. We evaluated lupus pregnancies that were followed and delivered from 2002 to 2016. Results: The average patient age was 29.1 ± 4.6 years, and the nulliparity rate was 45.2%. The disease flare-up occurred in 11.1% of patients. Lupus anticoagulants and anti-cardiolipine IgG and IgM antibodies were positive in 23.8%, 18.2%, and 18.2% patients, respectively. The average gestational age at delivery was 37.2 ± 3.7, and the average birth weight was 2813 ± 856 g. Fetal growth restriction, preeterm delivery, stillbirth, and preeclampsia rates were 16.6%, 10.3%, 10.3%, and 9.5%, respectively. A multidisciplinary approach to the care of pregnant women with SLE is mandatory for good maternal and fetal outcomes.

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