Özet:

The purpose of this study is to evaluate the anti-phungical effectiveness of Viburnum opulus L. (Gilaburu) fruit ethanol, methanol, ethyl acetate, chlorform and acetone extract on 45 Candida juice, isolated from urine samples. Fourteen Candida juice Ahi Evran University, Education and Research Hospital, is isolated from urine samples sent to the Microbiology Laboratory with a suspected infection. The fruit of Viburnum opulus L. (Gilaburu) is collected from the province of Kayseri and is prepared with ethyl acetate, ethanol, methanol, acetone, chlorform and water extract. Antifungal activity of the extract has been detected by the agar-coating method. The minimum inhibition concentrations (MICs) of the extract found to be effective by the Agar-cutting method are determined by the broth microdilusion method. 23 of the 45 Candida juices isolated from the urine samples are C. albicans and 22 are non-albicans. In the study, ethyl acetate and methanol extract were found to be more effective than 45 Candida juices in 29 and ethanol extract in 35. The MIC values of ethyl acetate, ethanol and methanol extract have been found between 500 μg/ml and 1500 μg/ml. The results of the study found that the fruit of Viburnum opulus L. has quite good antifungal activity on Candida juices that cause urinary infection from ethanol, methanol and ethyl acetate extract. This is the result of Viburnum opulus L. It is believed that fermented products can be recommended as a natural protector for persons with suspicious or high potential of urinary tract infection as an alternative to antifungal drugs.

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