Özet:

The aim of the work. Analysis of remedies assortment for substitution therapy of dry eye syndrome that are available on the pharmaceutical market of Ukraine. Materials and Methods. Marketing, statistical, structural, graphic. Results and Discussion. There are 11 drugs of the S01X A20 group – “Artificial tear fluid substitutes and other neutral drugs” and 24 registered as medical devices, including 1 multi-purpose solution (group 03. Ophthalmic and optical products), 16 ophthalmic products (group 03. Ophthalmic and optical products) and 7 solutions for washing, irrigation, treatment (group 13. Other products for treatment) among the remedies for local substitutive therapy for dry eye syndrome. An analysis of the remedies forms for substitution therapy showed that in Ukraine they are presented in four forms: eye drops, eye gel, solutions, emulsions. Assortment analysis by producing countries indicated a wide location of production capacities. The mechanism of action of these remedies is provided by the presence of active ingredients such as sodium hyaluronate, carbomer, hypromellose, carmellose, polyquad, povidone, polyvinyl alcohol, dexpanthenol with taurine, trehalose, a complex of vitamins with aminoacids, ectoin, omega-3, a combination of sodium hyaluronate with propyleneglycol and guar. Conclusions. 35 names of remedies are used in the form of eye drops, eye gel, solutions and emulsions for substitution therapy of dry eye syndrome in Ukraine. Almost 90 % of them are produced in 3, 5, 10 or 15 ml vials. The vast majority – 80 % – of remedies for substitution therapy of dry eye syndrome are imported to Ukraine from European countries. The composition of 17 items includes sodium hyaluronate as an active substance. Thus, it is worth to note the lack of remedies for the substitution therapy of dry eye syndrome in the form of ointments as a result of the conducted studies. In addition, attention should be paid both to the lack of remedies of this group of domestic production in general, and the limited range of active ingredients, represented only by carmellose sodium, taurine with dexpanthenol, and sodium hyaluronate.

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