Özet:

Acinetobacter baumannii (A. baumannii) is one of the most prominent hospital-borne pathogens encountered worldwide in health institutions, mostly at Intensive Care Units (ICU), which develops resistance to many antimicrobial classes. A. baumannii causes pneumonia, urinary tract infections, soft tissue infections, surgical site infections, catheter infections and bacteremia mostly in the ICU and inpatients. Infections, which develop with this pathogen are also often treatment-resistant. Epidemics arising from A. baumannii, which is resistant to various antimicrobial classes unfold through cross-infection of such 'reknown' sources as ventilators or the hands of health workers. The definition of multidrug-resistant (MDR) A. baumannii differs from that in the literature and country but still the common definition deals with strains, which are resistant to three or more groups of antibiotics. These groups of antibiotics can be carbapenems, aminoglycosides and fluoroquinolones. In this review, resistance mechanism and treatment options in MDR A.baumannii isolates will be discussed.

Anahtar Kelimeler: