Abstract:

The aim is to investigate the effect of melatonin on oxidative damage in rats exposed to Wi-Fi. This study aims to evaluate the effects of Wriless waves biophysically and biochemically. This study was to investigate the effects of Wi-Fi electromagnetic field (Wi-Fi-EMF) on total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) in various rat tissues. In this study, we used 30 male Wistar Albino rats of 230-250 grams of body weight. Animals were divided into five groups as control, saline (1 ml/kg/day olive oil for 30 days), Wi-Fi (12 hours/day for 30 days), melatonin (10 mg/kg/day for 30 days) and melatonin + Wi-Fi (10 mg/kg/day + 12 hours/day for 30 days). In thirtieth day, thirty min after the last drugs administration at the indicated doses, PTZ was administered 45 mg / kg to induce epileptic seizure. The animals were observed for 30 min. Seizure stages (according to the Racine Scale) and first myoclonic jerk times (FMJ). Twenty four hours after PTZ injection, kidney tissuss were collected for biochemical evaluation. Oxidative stress markers (total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI)) were measured in kidney tissues. In the control, no electromagnetic wireless exposure was applied. The quantities of TAS, TOS and oxidative stress index (OSI) in the collected kidney tissues were compared between the control and the exposure groups. Wi-Fi reduced antioxidant effect of melatonin (p<0.05). Moreover, Wi-Fi increased cell damage in kidney tissue (p<0.05). In terms of each parameter that is indicative for antioxidant levels and oxidant activity, there were significant differences between kidney tissues (P < 0.05). This is a original study, due to the fact that by revealing in length the Wi-Fi effects of oxidative damage on kidney tissues of rats. Wi-Fi studies show that Wi-Fi causes oxidative stress and apoptosis. Wi-Fi directly reduced the effect of melotonin. The effects of Wi-Fi are caused by oxidative means.

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