Objectives: Cognitive impairment is when a person has suffered recalling, learning new things, concentrating, or making decisions that affect his/her everyday life. Hypertension induces vascular alteration and lead to cognitive impairment by leading to hypoperfusion, ischemic and hemorrhagic stroke, and white matter injury. This study aimed to determine the prevalence and predictors of cognitive impairment among hypertensive patients on follow up at Jimma University Medical centre, Jimma, Southwest Ethiopia. Materials and Methods: Institution based cross sectional study design was employed from June 01 to July 15, 2018 among 279 hypertensive patients on follow-up at Jimma University Medical Centre chronic clinic, Jimma, Ethiopia. The collected data were cleared and entered into SPSS Version 20.0 for analysis. The association between the independent variables and the outcome variable (cognition level) was analyzed using logistic regression model. A p value of <0.05 was considered statistically significant in the final model. Results: Out of the 279 hypertensive patients included in this study, 142 (50.9%) were male and the remaining proportion was female. The mean age ± SD of the participants was 53.15 + 11.544 years with a range of 20 to 86 years. The prevalence of cognitive impairment in this study was 86 (30.8%). Triglycerides level > 200 mg/dL (AOR=3.570, 95% CI=1.598-2.977) and high blood pressure Stage II HTN were significantly associated with cognitive impairment (AOR=2.649, 95% CI=4.191-5.391). Conclusion: Cognitive impairment was relatively common in the study population. The study revealed that, high triglyceride levels and Stage II HTN were significantly associated with cognitive impairment.
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