Özet:

Wheezing is a high pitched polyphonic sound which occurred as a result of narrowing of the lower airways. The ‘wheezy infant’ is a complex situation which includes heterogen phenotypes and a group of diseases with different pathophysiological mechanisms. Three different wheezing phenotypes are defined according to age and sex of children, atopic backgroud, and patients’ risk factors. These 3 phenotypes are ‘transient early wheezing’, ‘non-atopic persistant wheezing’, and ‘atopic wheezing’ (asthma). Because the wheezing episodes seen in early years of life that might be the first sign of developing asthma, it is important to discriminate transient or persistant wheezing in infancy. Unfortunately, there are not any biochemical or genetic markers which can be used to predict the development of asthma in small children. Therefore, description of phenotypes of wheezing and establishment of appropriate treatment modalities are the most important approach to determine the progress of the disease

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