Özet:

Purpose: In patients with Hashimoto thyroiditis (HT), the changes in the macula, retina nerve fiber layer (RSLT) and central cornea thickness (SKK) are compared with the healthy control group suitable for life. Patients and Methods: The individuals who participated in the study were divided into 2 groups: Patients with HT diagnosis (group 1, n: 54 eyes) and healthy participants matched age (group 2, n: 70 eyes). Optical coherens tomography (OKT) measures cornea, retina and macular thickness. The average result measurements were SKK, eye pressure (GIB), central 1 mm foveal thickness (MFK), subfoveal coroid thickness (SFKK), total macular volume (TMH), central 1 mm foveal volume (SFH) and upper, nasal, lower and temporal layers. Results: The average GIB was 17.07 ± 2.34μm in group 1 and 14.20 ± 2.76μm in group 2 (p <0.001). The average number is 539. 44 ± 35.27μm and 555.06 ± 40.53μm (p = 0.001), SFKs were 227.35 ± 17.52μm and 230.38 ± 23.52μm (p = 0.57), SFKKs were 210,79 ± 20,13μm and 268,47 ± 24,56μm in Group 1 and Group 2 respectively, (p <0.001), TMHs were 7.16 ± 0.35mm3 and 7.02 ± 0.26mm3 (p = 0.07), CFVs were 0.17 ± 0.01mm3 and 0.19 ± 0.07mm3 (p = 0.16) respectively. In Group 1, the RSLT thickness values were found significantly thinner in all squares except the nasal square (p <0.05) (p = 0.086). The result: HT-related hypothyroidism can be a determining factor affecting the development of the cornea and retina. As the decrease in high GIB and RSLT thickness in children with HT increases the risk of developing glucoma, the decrease in SFKK may also create a tendency to develop koriorethinal disorders in the future.

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