Özet:

Purpose: Pempfigoid (BP) is a pempfigoid dermatoid caused by antibodies formed against the antigens found in the dermo-epidermal compound, often monitored in the age period. As a result of the inflammation caused by autoanticors, inflamatory mediators in the patient's serums and bulbs have increased and these increasing mediators may be associated with the severity of the disease. The neutrophil lymphocytes rate (NLO) is a parameter obtained by the division of the number of neutrophils into the number of lymphocytes, which has previously been studied in inflammatory diseases such as urethra, psoriasis, pemfigus vulgaris and cutanus vasculitis and has been found associated with the disease. In this study, it was studied whether NLR, a indicator of systemic inflammation, is a indicator that can be used in patients with BP. Patients and Method: Medical records of patients diagnosed with BP were examined between January 2013 and December 2017. The laboratory results in their files were evaluated; the average volume of thrombocytes (MPV), the number of neutrophils, the number of lymphocytes and the number of neutrophils were calculated by dividing the number of lymphocytes. Results: The study included 26 patients with BP and 25 control groups of patients. In patients with BP, the number of neutrophils (P = 0,005) and NLO (P = 0,04) was seen to be higher than the control group. The number of lymphocytes in patients with BP was not different from the control group. The result: Our study is the first study that studies the NLO as far as we know in patients with BP where the inflammation is involved in the etiopathogenesis. We consider that NLO, a parameter that can be easily calculated with the full blood count for systemic inflammation, can be a indicator that can be used in the diagnosis of BP.