Özet:

Rocuronium is a non-depolarizan neuromuscular blocker which gives middle or strong pain in high rate when it is used before induction to awake patients. In our study, our aim was to compare the effects of EMLA cream which is a mixture of topical local anesthetic with transdermal nitroglycerin (TNG) that has vasodilatation effect and with placebo on the patients who are planned for elective surgery. 18-75 year-old, fortyfive ASA grade I-III patients were randomly selected in 3 groups. One hour before the general anesthesia induction, in Group I 50 mg TNG (10 mg TNG/24 hours release patchs), in Group II, 1 gr EMLA cream and in Group III, 1 gr dexpanthenol cream were used. We evaluated the pain and sensation during the intravenously canulation and priming dose of rocuronium and also we evaluated the hand movements after the intubation dose of rocuronium. There wasn’t much difference after intubation dose of rocuronium between groups. In Group II, we showed that the pain and sensation after intravenously canulation and priming dose of rocuronium were significantly lower than in Group I and III. Our results indicate that using EMLA cream before priming dose of rocuronium is suitable but TNG isn’t a good choice.

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