Abstract:

In the review questions of changes of mucus structure and protective properties of mucosa as well as those of enteric nervous system (ENS) of mammalian gastrointestinal tract are discussed at aging. The resulted experimental and clinical data testify to presence of the various mechanisms providing reparative properties of mucosa. Enlarged susceptibility of mucosa to disturbing factors observed with the years is connected with changes of mucosal prostaglandins amount. Neurodegenerative processes in ENS strengthen with the years, thus various types of neurones are exposed to various kinds of degenerative changes. The causes of the latter remain insufficiently investigated by the present time. 

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