Abstract:

Target: Toxoplasma gondii (T. gondii), a compulsory cellular parasite, causes toxoplasmosis, is a zoonotic parasitic disease that is widely seen worldwide. In this study, the results of the T. gondii test were shared between January 2009 and May 2019. Here, the aim is to evaluate the results of T. gondii from the General Directorate of Public Health, the National Parasitology Reference Laboratory, between the years 2009-2019. Methods: This study examined the results of anti-T. gondii IgG, IgM, IgG avidite and Sabin-Feldman dye test (SFDT) from the serological methods used in the diagnosis for T. gondii. The ELISA method has been used for anti-T. gondii IgG, IgM and IgG avidite tests. SFDT, a reference test in the diagnosis of T. gondii, still retains its validity as a gold standard. In addition to the laboratory analyses, all the facts were given gender, age, year, year distribution, and sample type information. Results: 706 of the 2,778 matures evaluated in this study are men (25.4%) and 2,072 (74.6%) are women. When the anti-T. gondii IgG values were studied, 47.1% of all samples and 10.2% of anti-T. gondii IgM were positive. In SFDT, 1,228 (52%) of 2,361 patients were found positive. 319 of the 537 candidates (59.4%) and 909 of the 1,824 women (49.8%) were positive. In a ten-year study, the most common seropositivity tires of SFDT were at 1/64 levels. Anti-T in our work. When the gondii IgG, IgM and IgG avidite tests were evaluated all the facts in which the three were studied together in one patient, the IgG levels were found positive in all the facts studied in IgG avidite. In addition, 62.8 percent of 293 incidents with anti-T. gondii IgG values positive found high avidity, 24.2 percent limit values and 13 percent low avidity. In our study, when we assessed the events that occur together, both of them had an anti-T. gondii IgG seropositivity of 80%, and both of them had an anti-T. gondii IgM seropositivity of 5%. These high rates support the transfer of antibodies between the mother and baby. When examined the provincial distribution where the samples came, it was found that the maximum number of events came from Ankara with 80.7%. The most sent sample type is the blood sample, and in the second frequency the brain is detected as the spinal fluid. The result: T. gondii preserves its importance for public health today due to its high positivity rates. This study, which has collected data for ten years, has shown that, despite increased awareness, high seropositivities are still predicting. Therefore, the systematic collection and evaluation of the laboratory analysis results for the diagnosis of toxoplasmosis will contribute to the adoption of control measures.

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