Abstract:

Medicinal plants have been considered as an important source for the prevention and treatment of various diseases. The genus Arnica L. is a genus of Asteraceae family, many species of which are used in traditional medicine. Arnica chamissonis Less. and Arnica foliosa Nutt., which belong to plants of the genus Arnica L., are successfully grown in the culture. There is insufficient information in the literature on the biologically active substances of Arnica foliosa Nutt. The presence of sesquiterpene lactones in the leaves and inflorescences is indicated. The flowers contain polysaccharides, monosaccharides, which mainly contain D-glucose and D-xylose, as well as phenolic compounds (quercetin, luteolin, kaempferol) and essential oils. The aim. The aim of our study was to identify and determine the quantitative content of fatty acids by gas chromatography/mass spectrometry method (GC/MS) in Arnica foliosa Nutt. herb. Materials and methods. The determination of fatty acids composition of Arnica foliosa Nutt. was carried out by gas chromatograph Agilent 6890N with a mass detector 5973 inert (Agilent Technologies, USA). Results. The analysis of Arnica foliosa Nutt. herb showed a mixture of saturated (1.61 mg/g; 48.79 %) and unsaturated (1.69 mg/g; 51.21 % from total content acids) fatty acids. The main components of Arnica foliosa Nutt. herb were palmitic (1.02 mg/g; 30.91 % from total content acids), linolenic (0.96 mg/g; 29.09 % from total content acids) and linoleic (0.67 mg/g; 20.30 % from total content acids) acids. This raw material is a source of essential fatty acids, such as omega-3 (linolenic acid) and omega-6 (linoleic acid). Conclusions. As a result of Arnica foliosa Nutt. research, the presence of fatty acids is established in its raw material. The dominant fatty acids in the studied raw material were palmitic, linolenic and linoleic acids, the content of which was 30.91 % (1.02 mg/g), 29.09 % (0.96 mg/g) and 20.30 % (0.67 mg/g) from total content acids, respectively. The result shows that Arnica foliosa Nutt. is the source of fatty acids, so the use of this plant raw material for new remedies is possible in the future Author Biographies Liliia Budniak, І. Horbachevsky Ternopil National Medical University of Ministry of Health of Ukraine Voli ave., 1, Ternopil, Ukraine, 46001 PhD, Assistant Professor Department of Pharmacy Management, Economics and Technology

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