Özet:

Objectives: Several mucocutaneous diseases are responsible for desquamative gingivitis (DG) and diagnostic delays are common in these diseases due to non-specific clinical oral presentations. The present study aimed to analyze the clinical features of DG-related mucocutaneous diseases with oral manifestations and compare the findings with previous reports. Materials and Methods: Thirty newly diagnosed patients with oral mucocutaneous disease in the Dermatology and Venereology Department of Akdeniz University Medical School, between January 2018 and January 2020, and referred to the Periodontology Department for periodontal treatment were evaluated retrospectively. Patients demographic data (age and gender), medical comorbidities, primary lesion site (oral or skin), and clinical features of gingival and oral lesions (location and symptoms) were examined. Results: There were 18 oral lichen planus (OLP), 8 pemphigus vulgaris (PV), and 4 mucous membrane pemphigoid (MMP) patients with oral involvements. The mean age of the patients was 50.03 ± 9.71 years with a female predominance (male to female ratio 1:1.7). All patients suffered from chronic burning sensation and oral pain. DG was detected in all three mucocutaneous diseases but OLP was the main disease associated with DG (60%). However other oral mucosal lesions and extraoral involvements were more frequent in PV patients. Conclusions: According to these results, OLP, MMP, and PV are the mucocutaneous diseases responsible for DG, and OLP is the most common cause of DG. Clinicans should be familiar with the clinical presentations and signs (patient complaints) of DG-related mucocutaneous disease for early diagnosis, proper treatment, and quality of life of the patient.

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