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Amaç: Fetal dönemde intrakardiyak ekojenik odağın (İKEF) önemi tartışmalıdır. İKEF’nin fetüste kardiyak malformasyon veya anomali riskini etkileyip etkilemediğini belirlemek için mevcut çalışma gerçekleştirildi. Gereç ve Yöntemler: Aralık-2016 ile Mayıs-2019 tarihleri arasında çocuk kardiyoloji bölümüne fetal ekokardiyografi için yönlendirilen 248 intrakardiyak ekojenik odak saptanan fetüse ait özellikler retrospektif olarak incelendi. İKEF sayısı, yerleşim yeri, büyüklüğü, yapısal kardiyak anomali varlığı incelendi. İstatistiksel analiz için χ2 veya Fisher exact testi yapıldı. Bulgular: İKEF’a sahip 248 fetüsün 10 unda kardiyak patoloji saptandı. Kardiyak anomali görülme prevelansı %4 olarak belirlendi. En sık tespit edilen kardiyak anomali ventriküler septal defektti. Ekojenik odağın yerleşimi en sık sol ventrikül (LV) (% 84.3) yerleşimli, ardından biventriküler (BV) (%9.7) yerleşimli ve 6 sağ ventrikül (RV) yereşimliydi. RV yerleşimli İKEF’si bulunan fetüslerde kardiyak anomali prevelansı LV ve BV yerleşimli İKEF bulunanlara göre anlamlı olarak yüksekti (sırasıyla % 13.3’e karşı %3.3 ve %4.1). Tüm fetüslerin %14.5’inde birden fazla İKEF vardı. İKEF varlığı ile anne yaşı arasında istatistiksel olarak anlamlı bir fark bulunmadı (p = 0.87). Sonuç: Özellikle sağ ventrikülde İKEF’si olan fetüslerde daha sık kardiyak yapısal anomali tespit edildi. Sağ ventrikülde fetal ekojenik odağın histopatolojik özelliklerini incelemek için daha fazla araştırma yapılması gerekir.
Objective: In the fetal period, the importance of intrakardial ecogenic focus (ICEF) should be discussed. Current study was conducted to determine whether ICE affects the risk of heart malformation or abnormality in the fetus. Tools and Methods: The characteristics of the detected fetus in 248 intrakardial ecogenic focus, directed to the child's cardiology department for fetal ecocardiography between December 2016 and May 2019, were retrospective examined. The number, the location, the size, the presence of structural cardiovascular anomalies have been studied. For statistical analysis, the χ2 or Fisher exact test was performed. The findings: In 10 of 248 fetuses with ICEF, heart disease was detected. The prevalence of cardiovascular anomaly was estimated at 4%. The most frequently detected cardiac anomaly is ventricular septal defect. The eco-genic center was located in the left ventricle (LV) (84.3%), then in the biventricle (BV) (9.7%), and 6 right ventricle (RV) was located in the ground. The prevelence of cardiovascular anomaly in the fetus with RV-instated ICE was significantly higher compared to those with LV and BV-instated ICE (3.3% and 4.1% respectively against 13.3%). In 14.5 percent of all fetuses there was more than one ADHD. There was no statistically meaningful difference between the presence of the IMF and the age of the mother (p = 0.87). The result: Heart structural anomalies were more frequently detected in fetuses, especially in the right ventricle. Further research is needed to study the histopathological characteristics of the fetal ecogenic focus in the right ventricle.
Objective: The significance of intracardiac echogenic focus (ICEF) in the fetal period is controversial. We conducted the current study to determine whether ICEF affects the risk of cardiac malformation or anomaly in the fetus. Material and Methods: The characteristics of the fetus with 248 intracardiac echogenic foci referred to the pediatric cardiology department for fetal echocardiography between December-2016 and May-2019 were retrospectively analyzed. The number, location, size of ICEF and presence of structural cardiac anomaly were examined. For statistical analysis, χ2 or Fisher’s exact test was used. Results: Cardiac anomaly was detected in 10 of 248 fetuses with ICEF. The prevalence of cardiac anomaly was 4%. The most common cardiac anomaly was ventricular septal defect. The most common location of the echogenic focus was left ventricular (LV) (84.3%), followed by biventricular (BV) (9.7%) and right ventricular (RV) placement of 6%. The prevalence of cardiac anomalies in fetuses with ICEF located in RV was significantly higher than those with ICEF with LV and BV (13.3% vs. 3.3% and 4.1%, respectively). 14.5% of all fetuses had more than one ICEF. There was no statistically significant difference between the presence of ICEF and maternal age (p = 0.87). Conclusion: Cardiac structural anomalies were found more frequently in fetuses with ICEF, especially in the right ventricle. More research is needed to examine the histopathological features of fetal echogenic focus in the right ventricle.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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