Abstract:

DOI: 10.26650/IUITFD.345626 Purpose: In this study we studied the contribution of SPECT-BT to the planned imaging in post-treatment imaging in patients with difference papillary thyroid cancer (DTK). Average and Method: A total of 325 patients with DTK diagnosis operated and radioactive iodine therapy (100-200mCi) were post-treatment (254 women, 71 men; age range: 15-81). All patients have planned + SPECT-BT images from the neck-toraks area with all the body planners. In addition, the planned images have been viewed SPECT-BT from the fields identified with suspicious attitudes. The planar images classified as benign, suspicious and malicious, the iodine positive fields were re-evaluated by two nuclear medical specialists with SPECT-BT images. The final diagnosis was confirmed by histology, other imaging methods, clinical-serological tracking. Results: According to patient-based results, SPECT-BT planned imaging in addition to 21 (21/50) metastatic lymph nodes in patients, 2 (2/10) lung metastases in patients, 2 (2/12) bone metastases in patients; 83 in patients benign, 48 in patients malign, the planned imaging interpretation changed by clarification of suspicious attitudes.   Sensitivity, specificity, positive predictive values, negative predictive values and accuracy were calculated as 63.4%, 92.7%, 67.7%, 91.3%, and 99.3%, respectively for SPECT-BT, 96.8%, 100%, 99.2 and 99.3%, respectively. SPECT-BT affected the treatment management of a total of 76 patients (23.3%). The result: SPECT-BT screening improves the diagnosis accuracy by reducing the negative/positive results of planned screening in post-treatment screening in DTC patients. Our findings suggest that SPECT-BT viewing should be taken into the routine viewing protocol in the assessment of the neck and throat area metastasis by DTC.

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