Abstract:

This open-label non-controlled study is to evaluate the effects of black vinegar intake for 8 weeks on the anthropometric measures, cardiometabolic profiles, and insulin sensitivity among impaired fasting glucose adults. 32 subjects (14 males and 18 females) were recruited with the mean age of 56.3 (from 25 to 65). Black vinegar 50 ml was diluted to 500 ml with drinking water and was given to all subjects for 8 weeks. At baseline and 8-week, all study subjects received 75 g of oral glucose tolerance test (OGTT) after 10 h of fasting. Venous blood was collected at 0, 30, 60, 90 and 120 min. Plasma glucose and insulin levels were measured using the glucose oxidase method and radioimmunoassay method. Anthropometric variables, blood pressure and blood lipid profiles were measured using standard methods. The Wilcoxon signed-rank test was used to compare the difference between baseline and after eight weeks. After eight weeks, the body weight and BMI decreased from 68.2 ± 14.4 kg to 67.6 ± 14.2 kg and 26.3 ± 4.5 kg/m2 to 26.0 ± 4.4 kg/m2, respectively, with statistical significance (p < 0.05). Triglyceride level decreased from 152.5 ± 134.7 to 140.6 ± 93.8 mg/dl but without statistical significance. The blood glucose levels at 120 min of OGTT decreased from 178.8 ± 57.0 to 173.7 ± 57.5 mg/dl and the insulin levels at 120 min of OGTT increased from 117.5 ± 74.2 to 126.4 ± 95.9 IU/L but not statistically significant (p > 0.05). There is a slight decrease of body weight and BMI, but no significantly change in blood pressure, lipid profiles, and insulin sensitivity after eight weeks of black vinegar intake among impaired fasting glucose adults. However, further large-scale and longer studies are needed to explore the effects of black vinegar on cardiometabolic profiles and insulin sensitivity.

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