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Retina Ven Tıkanıklığına Bağlı Gelişen Maküla Ödeminde İntravitreal Bevacizumab Enjeksiyonu Sonuçları
2019
Journal:  
Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi
Author:  
Abstract:

Amaç: Retina ven tıkanıklığına bağlı oluşan maküla ödemi tedavisinde intravitreal bevacizumab enjeksiyonu sonrası görme keskinliği ve santral fovea kalınlığı değişikliklerini incelemek. Gereç ve Yöntem: Bu retrospektif çalışmaya retina ven tıkanıklığına bağlı maküla ödemi tanısı alarak takip edilen intravitreal bevacizumab enjeksiyonu uygulanan 21 hastanın 21 gözü incelendi. Olgulara birer ay aralıklarla izlenerek 3 doz intravitreal 1.25 mg/0.05 mL bevacizumab enjeksiyonu uygulandı. Görme keskinliği (GK), santral fovea kalınlıkları (SFK) ve komplikasyonlar kayıt edildi. Verilerin karşılaştırılmasında t-test kullanıldı, P<0.05 değeri istatistiksel olarak anlamlı kabul edildi. Bulgular: Hastaların genel yaş ortalaması 62.14±9.4 yıl (46-84) idi. Hastaların enjeksiyon öncesi santral fovea kalınlığı ortalaması 548.0±227.8 μm iken, enjeksiyon sonrası 1.ay 272.8±128.6 μm ve 3.ay 269.6±125.7 μm olarak bulundu. Preoperatif santral fovea kalınlıgına göre, tedavi sonrası 1.ay ve 3.ay santral fovea kalınlıklarında azalma saptanmıştır. SFK'da görülen tüm bu azalmalar istatistiksel olarak anlamlı tespit edilmistir (P<005). Hastaların enjeksiyon öncesi görme keskinligi ortalaması 0.72±0.45 logMAR (0.10–2.0) iken, enjeksiyon sonrası 1.ay 0.39±0.41 logMar (0.0–1.1) ve 3.ay 0.41±0.38 logMar (aralık; 0.0–1.3) olarak bulundu. Sonuç: Hastaların enjeksiyon öncesine göre 1. ayda ve 3. ayda en iyi düzeltilmiş görme keskinliği (EİDGK) istatistiksel olarak anlamlı bir artış vardı (P<0.05).

Keywords:

The results of the Intravitreal Bevacizumab Injection in the Progressive Macula Payment Related to Retina Venus Injection
2019
Author:  
Abstract:

Purpose: In the treatment of macular inflammation, which is linked to retina venous blocks, the intravitreal bevacizumab injection examines changes in vision severity and central fovea thickness. Tools and Methods: This retrospective study examined 21 eyes of 21 patients who were administered intravitreal bevacizumab injection followed by the diagnosis of retina venous injection. The incidents were monitored in intervals of one month and 3 doses of intravitreal 1.25 mg/0.05 mL bevacizumab injections were administered. Vision sharpness (GK), central fovea thickness (SFK) and complications were recorded. The t-test was used to compare the data, and the P<0.05 value was statistically meaningful. The average age of patients was 62.14±9.4 years (46-84). The patient's pre-injection central fovea thickness was 548.0±227.8 μm, while the patient's pre-injection central fovea thickness was 1 month 272.8±128.6 μm and 3 month 269.6±125.7 μm. According to the preoperative central fovea thickness, a decrease in the 1st and 3rd months of central fovea thickness has been observed after treatment. All of these reductions in the SFK are statistically meaningful (P<005). The patient's pre-injection visual accuracy was 0.72±0.45 logMAR (0.10−2.0) while the patient's pre-injection visual accuracy was 0.39±0.41 logMar (0.0−1.1) and the patient's pre-injection visual accuracy was 0.41±0.38 logMar (December; 0.0−1.3). The result: Patients had a statistically significant increase in the best corrected vision accuracy (EIDGK) in the 1st and 3rd months compared to before the injection (P<0.05).

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Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi

Field :   Sağlık Bilimleri

Journal Type :   Ulusal

Metrics
Article : 643
Cite : 2.196
2023 Impact : 0.048
Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi