Abstract:

Objective: To evaluate indications, maternal and gestational age distribution, invasive methods, and karyotype results of chorion villus sampling (CVS) procedures Material and methods: CVS results performed for karyotyping in high-risk pregnancies at Suleyman Demirel University obstetrics and gynecology clinics between January 2008- February 2013 were retrospectively investigated. Results: Forty-two cases were included. Maternal age was between 18-25 years in 19%, 26-33 years in 36%, and 34-41 years in 45%. Mean gestational week at the procedure was 11.2 ± 1.2 (range, 11-15 weeks). A chromosomal abnormality was detected in 35.7% (n=15) of the cases. There were no fetal losses during or after 72 hours of the CVS procedures. Conclusion: CVS is a valuable and relatively safe method for the detection of chromosomal abnormalities at early gestation.

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