İndirme
1
In this report we presented the case of an adolescent male who noticed bloody spots on his underwear after the dose increase during his osmotic-controlled release oral delivery systemmethylphenidate (MPH) treatment. This symptom disappeared when the MPH treatment was discontinued, was not reported with atomoxetine monotherapy, but reoccurred with combination treatment using atomoxetine and increased doses of immediate-release MPH. We discussed the clinical picture and the possible pathophysiological mechanisms for this adverse effect.
Here we report a case of an adolescent boy who developed bloody spots on his underwear with increasing dosage of osmotic-controlled release oral delivery system (OROS) MPH. This symptom did not occur with atomoxetine monotherapy but occurred with atomoxetine and increased dosage of immediate release MPH combination. We plan to discuss the clinical picture and possible pathophysiological mechanisms of this adverse effect.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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