Özet:

Purpose: This study aimed at assessing the conformity of the Gleason scores and grade group classifications that are important in the prognosis, comparing injective biopsy (IB) and radical prostatectomy (RP) materials in the prostate adenocarcinoma. Tools and Methods: In the Medical Faculty of Medicine of Kırıkkale University, in the Department of Anabilities of Medical Patology, between 2013-2018, 42 pieces of the patient's RP and IB materials, who have been diagnosed with prostate adenocarcinoma, were histopathologically evaluated. Results: The average age of 42 incidents in the study was 61.1 (48-79) and the serum PSA levels were 4 ng/ml (0.03-26.320 ng/ml). In thirty cases, IB and RP Gleason scores were individually identified, and in 12 cases, 1 grade score was identified according to the difference. Similarly in the RP material 6 (%14,2) in the patient’s grade group score is reduced according to IB (low score, down-grade), 8 (%19) in the patient’s increase (high score, up-grade) is determined while 28 (%66,6) in the patient’s individual adaptation is determined. In RP and IB samples, statistically significant consistences were found when compared Gleason (p<0,001, cappa=0.524) and grade group (p<0,001, cappa=0.490) scores. Result: The full conformity rates in Gleason scores given to IB and RP materials in literature were between 28.2-68%. In this study, a high level (71.4%) of compatibility compared to literature between the examples of IB and RP studied. The main causes of Gleason scores incompatibility between IB and RP examples were considered as the multi-called distribution of the tumor, inter-observator incompatibility and the narrowness of Gleason scores range.

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