Özet:

We aimed to introduce a case of peripheral ulcerative keratitis occuring after cross-linking for the treatment of keratoconus in this study. A female diabetic patient, 38 year-old, was admitted to our clinic in September 2011. Her cycloplegic refraction was -1.00 -3.75 48 in her right eye and -2.00 -4.50 144 in her left eye. Her visual acuity was 0.4/ 0.1 with and without correction. Her keratometry was measured as  46.12 50.62 139 in her right eye and 46.75 53.62 54 in her left eye. After 17 months she was admitted to our clinic again and she gave a history of cross-linking in her both eyes 3 weeks ago. The patient complained of pain, blurry vision and hyperemia in her both eyes. She had been treated with antibiotic drops, artificial tears, corticosteroid drops and contact lenses for 4 monthts, but no improvement could be recorded. In contrast epithelial defects, infiltrates and thinning were detected in the periphery of both corneas. Because the systemic steroids caused dysregulation of blood glucose level, Azathioprine was preferred. Pathologic findings ameliorated with this drug, but it had to be stopped because of economical reasons. The complaints recur sometimes and are treated with topical drugs. The patient stil has a ring opacity in her both eyes. The doctors interested in the cross-linking treatment of keratoconus should be careful about the diabetes mellitus. If peripheral ulcerative keratitis is detected in such a case it can be treated with systemic immune suppressive drugs.

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