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DOI: 10.26650/IstanbulJPharm.2019.19013 Chemical composition of volatile oils obtained from the roots, fruits and aerial parts of Glaucosciadium cordifolium (Boiss.) B.L.  Burtt&P.H. Davis (Apiaceae) were analyzed using gas chromatography-flame ionization detector/mass spectrometry, simultaneously. Furthermore, antimicrobial and antioxidant activities of G. cordifolium volatile oils were investigated for possible utilization.  Total of 62 volatile compounds were identified in G. cordifolium essential oils, where the main component was characterized as α-pinene in all parts, commonly. The other main components were β-pinene (15.7%), (Z)-β-ocimene (14%) and sabinene (7%) in the volatile oil of the aerial part; sabinene (10.1%), β-pinene (10.1%) and α-phellandrene (5.3%) in the essential oil of the fruits; hexadecane (12.2%), tetradecane (11.9%), octadecane (7.4%) in the essential oil obtained from the root, respectively.  The in vitro microdilution method was used for the antimicrobial activity testing against Salmonella typhi ATCC 6539, Acinetobacter baumanii ATCC 19606, Bacillus cereus ATCC 14579, Staphylococcus aereus ATCC 6538, Listeria monocytogenes ATCC 19115, Helicobacter pylori ATCC 43504 and Mycobacterium avium ATCC 25291. The best antimicrobial activity of the volatile oils was against L. monocytogenes among the tested microorganisms. In addition, DPPH•-ABTS• scavenging activity was tested, none of the essential oils showed any significant antioxidant activity.   Cite this article as: Karadağ AE, Demirci B, Çeçen Ö, Tosun F (2019). Chemical characterization of Glaucosciadium cordifolium (Boiss.) B. L.  Burtt & P. H. Davis essential oils and their antimicrobial, and antioxidant activities. Istanbul J Pharm 49 (2): 77-80.

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