Abstract:

Portal vein thrombosis is one of the causes of portal hypertension. Portal vein thrombosis can be a cause slowly and well tolerance, and severely and mortal. Thrombophilia, forming tendency of thrombosis is a term that describes situations. Thrombophilia is not a very common phenomenon and has acquired or congenital causes. Inherited  thrombophilic abnormalities  may have a role in the development  of portal vein thrombosis. These include the Factor V Leiden and prothrombin 20210A mutation, protein S, C, and antithrombin 3 deficiency is the most common and known thrombophilic patients are questioned as to why the most common etiological factor. In this case presentation,  we report a 37 year old woman patient with portal vein thrombosis and to apply our clinic with liver cirrhosis that outcome MTHFR homozygous  gene mutation.

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