Özet:

Aim The aim of this study was to investigate the effect of low molecular weight heparin (LMWH) use on inflammatory markers. Material and Methods: Fifty-seven pregnant women were enrolled in this study. Neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), lymphocyte monocyte ratio (LMR), and systemic immune-inflammation index (SII) (Neutrophil x Platelet / Lymphocyte) were calculated using complete blood count parameters. These parameters were compared before and after one month usage of LMWH. . Results After the usage of LMWH , mean erythrocyte distribution width (RDW), mean platelet volume (MPV), mean platelet distribution width (PDW) , NLR, and SII increased and platecrite, and LMR decreased significantly (p <0.05). Also, there was no change in TLR. Conclusion In order to see anti-inflammatory effect of LMWH easily and cost effectively MPV, PDW, platecrite may be used. These parameters might be helpful in LWMH prescribed patient follow-ups. LMWH might be associated with better pregnancy outcomes as a result of both anticoagulation and anti-inflammatory effects.

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