Abstract:

Introduction: Brucellozis is still a common infectious disease in our country and sometimes it may be presented with uncommon clinical manifestations.Case 1: A ten years old male was presented to our clinic with complaints of malaise,weight loss, petechia, and bleeding of gums. On physical examination cervical lymphadenopathy and hepatosplenomegaly had been detected and in complete bloodcount pancytopenia was found.admitted to our clinic. In bone marrow aspiration hypocellular bone marrow was seen. His Brucella agglutination test was positive at1:1280 titer and the blood culture was positive for Brucella mellitensis. The pancytopenia was resolved after the antibiotherapy. Case 2: A nine-year-old female was referred to our clinic with tachycardia, who hadthe cardiac rate of 136/min. The electrocardiography showed sinusal tachycardia andechocardiography was normal, no endocarditis or pericarditis was present. She hadcomplaints of fatigue and lassitude for the last month. Her brucella agglutination testwas positive at 1:1280 titer and blood culture was negative. After antibiotherapy hersymptoms regressed, cardiac rate decreased to 80-100/min. Isolated tachycardia maybe the early manifestaion of brucellosis in children which has not been reported previously. Conclusion: Brucellosis is a rare cause of pancytopenia, it should be considered in differential diagnosis with pancytopenia of children. Brucellosis was known to be involved cardiovascular system, but tachycardia which was not due to fever as theonly sign of disease has not been reported previously made our case very interesting

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