Abstract:

In solvents with increased polarity such as Alchemilla persica, hexane, dicloromethan, ethyl acetate, methanol and water, plant extracts with different polarities were obtained. In the determination of antioxidant activity, the total phenol content, the total flavonoid content and the likopen content are determined as high compared to the other extracts in the ethyl acetate, the phenolic acid content in the hegzan extract; the β-carotene content is determined as high compared to the other extracts in the methanol extract. Total antioxidant activity, DPPH free radicals elimination activity, metal shelling capacity, total deduction power, hydrogen peroxide elimination, hydroxyl radicals elimination activities are determined in different concentrations. In determining antimicrobial activity, the agar disk diffusion technique was used. In antimicrobial tests, Alchemilla persica's dicloromethane extract was determined as the highest activity extract..The antimicrobial properties of ethyl acetate extract were almost similar to the dicloromethane extract. These extracts were followed by methanol and water extracts in antimicrobial assessment. As a result of antioxidant studies with different extracts of Alchemilla persica, it has been found to be more effective than standard antioxidants such as α-tokoferol, BHA, BHT and Trolox. Water and methanol extract from plant extracts have been studied for anti-citotoxic effects and these extracts have prevented cell growth in different concentrations. The results of the study have found that the extract of this Alchemilla persica species has antioxidant, antimicrobial and antisitoxic effects. Keywords: Alchemilla persica., Anti-toxic Activity, Antioxidant Activity, Antimicrobial Activity, Plant Extract.

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