Objective: Sudden sensorineural hearing loss (SSNHL) is defined as hearing loss of at least 30 dB or more in three contiguous frequencies, occurring within 72 hours. Based on the association of increased whole blood viscosity (WBV) markers as a prognostic indicator in vascular disorders, we aimed to determine the association between whole blood viscosity (WBV) and sudden sensorineural hearing loss (SSNHL) prognosis. Material and Methods: In this retrospective study, 73 patients diagnosed with SSNHL were included. The WBV calculation was performed via validated formula by using hematocrit (HCT) and total plasma protein (TP) concentrations at high shear rate (HSR=208/s) and the low shear rate (LSR=0.5/s). Pre- and post-treatment pure-tone average (PTA) results were recorded. In addition mean values of LSR and HSR were compared between patients and healthy control group. Results: In the patient group, 54.8% were affected in the right ear and 45.2% in the left ear. Of the patients, 35.6% (n=26) were resistant to treatment (to Siegel criteria type 4). The higher mean HSR and LSR values in patients with treatment-resistant and severe SSNHL were not statistically significant. No statistically significant difference was found between the patient and control groups according to the WBV values. Conclusion: Blood viscosity LSR and HSR markers had no predictive value on SSNHL prognosis. However, it should be considered that direct measurement of WBV instead of measurement with a formula may cause different results.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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