Özet:

Because viruses are cellular mandatory parasites and many viral families have different replication strategies, they are closely related to cellular organic and functional compared to other microorganisms, and they have effects on these mechanisms. These effects are also, without a doubt, the mechanisms of cell death. In replication-patogenesis studies with viruses, many studies on apoptosis and necrosis as cell death have been done. Autophagia has not been much evaluated in viral infections until the last few years, but with its appearance the relationship with viral infections has begun to be investigated. Autophagia ("Auto" and "Phagy"; the word means "eat yourself"); is a catabolic process that cells use to protect themselves from disappearance in various stress situations and to continue hemostasis, and the cell obtains the energy it needs in this process by digesting its own resources. Otophagia is a physiological event that is formed by the formation of vesicles with a double layer membrane in the organism and has three kinds of macro, micro, chaperon-related autophagia that have been defined so far. As a result of the rapid increase in the number of studies related to autofagia and viral infections in recent years, the interaction between autofagia and viruses has attracted interest as the subject of research for many types of viruses found in the DNA or RNA virus family. The question of how viruses use the autophagia mechanism to escape immunological response and continue their viral life cycles and question the place of autophagia in the molecular mechanisms of viral pathogenesis is the basic study subjects. According to the research, there is a relationship between autofagia and viruses that can be compared to a sharp knife on both sides. Unlike apoptosis and necrosis of the cell death mechanisms, this physiological event triggers a series mechanism that the residential cell has launched in order to get rid of some pathogens, as it appears as a response to the cell’s stressed nutritional needs. Even this event is used as a way that will be in their own benefit by viruses; to be able to start or continue their replications and to help form viral coverings. This collection contains information to understand the relationship between this physiological event and viruses; the autofagia mechanisms, the used pathways, the proteins that trigger and trigger autofagia, how autofagia is used by various viruses (in the case of interaction between a single virus or two viruses from the same family).

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