Let $R$ be a prime ring with extended centroid $C$ and maximal left ring of quotients $Q_{ml}(R)$. For a nonzero element $b\in R$ let $F:R\rightarrow R$ be a right generalized $b$-derivation associated with the map $d$ of $R$. Suppose that $s\left(F(x)\right)^n=0$ for all $x\in R$ where $s$ is a nonzero element in $R$ and $n\geq 1$ is a fixed positive integer. Then there exist some $c\in Q{ml}(R)$ and $\beta \in C$ such that $d(x)=ad_c(x)$, $F(x)=(b+\beta)xb$ for all $x\in R$ and either $s(c+\beta)=0$ or $b(c+\beta)=0$.
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