Özet:

Objective: To follow up the postoperative serum osmolarity values and to investigate the risk of inappropriate ADH syndrome development following neck dissection. Material andMethods: This study was conducted in Umraniye Research and Education Hospital Ear-Nose and Throat Clinic between June 2010 and October 2011. Thirtyone patients who underwent neck dissection with unilateral ligation of the internal jugular vein (Group 1) or without ligation of internal jugular vein (Group 2) due to head and neck cancer were enrolled in the study. The osmolarity values were detected preoperatively and 7 days postoperatively on a daily basis. Early osmolarity changes in groups and the risk of development of inappropriate ADH syndrome were reported. Results: Eleven (35.5%) of 31 patients (Group 1) underwent neck dissection with ligation of internal jugular vein, 20 (64.5%) patients (Group 2) underwent neck dissection without ligation of internal jugular vein. There has been a statistically significant decrease in postoperative osmolarity values in group 1 (p=0,043). However, only 1 patient developed early inappropriateADH syndrome.Also, there has been a statistically significant decrease in postoperative osmolarity values in group 2 (p=0,006). None of the patients in group 2 developed inappropriateADH syndrome.Although, unilateral ligation of the internal jugular vein resulted in postoperative decrease in serum osmolarity, it did not have a statistically significant effect on the development of inappropriate ADH syndrome. Conclusion: Our study shows that neck dissection is not an increased risk factor for the development of inappropriate ADH syndrome. Also, the comparison of postoperative decrease in osmolarity values between the patients undergoing neck dissection with ligation of the internal jugular vein and the patients without ligation of the internal jugular vein did not reveal significant difference.

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