Abstract:

AIM: Tc-99m DMSA scintigraphy is a reliable, sensitive and frequently preferred method in both the detection of renal defects and the calculation of differential renal function. In this study our aim was to compare the effi ciency of the Tc 99m MAG3 with the Tc 99m DMSA in the evaulation of renal parenchymal diseases of the pediatric age group. METHODS: Following the determination of at least one hypoactive region, a hypoactive defect and/or a decrease in renal cortical uptake in Tc-99m DMSA scan, the renal paranchyma was evaluated qualitatively and quantitatively by using Tc-99m MAG3 scintigraphy. By qualitative assessment, compliance/non-compliance of the 206 kidneys were evaluated. The initial renal extraction functions were calculated by using the Tc-99m MAG3 scintigraphy. Both methods were evaluated statistically. RESULTS: The study included 61(59%) female and 42 (41%) males with a mean age of 8.8 ±3.2 years. The contributions of the left and the right kidneys to the total renal function with the Tc-99m DMSA scintigraphy were as 50.1521.07 and 49.85±21.08, respectively. The contributions of the initial left and right renal extraction functions with the Tc-99m MAG3 were as 51.10±22.00 and 48.90±22.01, respectively. The two scintigraphy techniques were signifi cantly correlated (r=0.990,p=0.001). There were 155 (75.25%) compliant kidneys and 51 (24.75%) kidneys with hypoactive regions/scars or decreased uptake. CONCLUSION: There was a positive correlation between the Tc-m99m DMSA and the the Tc--99m MAG3 reanl functional assessments

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