Abstract:

Abstract Pilonidal sinus is an acquired and well described disease which is mostly located in sacrococcygeal midline region, lined by squamous epithelium and characterized by chronic inflammation including foreign body giant cells and sinus or sinuses containing epithelial debris and sometimes young granulation tissue. A malignant transformation can be seen in 0.1% of chronic or recurrent pilonidal sinus disease. The present case was 63 years old male patient undergoing pilonidal sinus operation 35 years ago. In the physical examination, there was an ulcerovegeteting mass of 10 cm in diameter, including multiple orifices of sinuses that contained purulent material drained by squeezing. The histopathological examination of the mass resected with wide excision revealed a typical verrucous squamous cell carcinoma. There were no lymphovascular and perineural invasions, also any distant metastases was observed in this case. Keywords: Pilonidal sinus, squamous cell carcinoma, carcinomatous transformation

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