Özet:

Objective: Microscopic urine sediment examination is necessary for evaluation of renal and urinary tract diseases. In this study, we evaluated and compared analytic and diagnostic performances of the DIRUI FUS-200 and a new image-based automated urine sediment analyzer Urised 3. Method: 440 urine samples submitted to our laboratory were evaluated by two automated urine sediment analyzers and standardized manual microscopy. Precision, linearity and method comparison studies were performed according to CLSI guidelines. Results: The correlation coefficients for erythrocyte (RBC) and leukocyte (WBC) counts between the FUS-200 and manual microscopy were 0.993 and 0.861; the Urised 3 and manual microscopy were 0.962 and 0.818; the FUS200 and Urised 3 were 0.961 and 0.961, respectively. Clinical non-concordance ranged from % 7 to % 14.16 between all methods. Conclusions: The concordance among the analyzers and manual microscopy for WBC was better than for RBC. The concordance between the analyzers was better for WBC and RBC. Although the UriSed 3, FUS-200 and manual microscopy counts were in agreement, confirmation of the automated methods’ results by manual microscopy is helpful, particularly for pathological samples near the cutoff values.

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